Employees of the Novosibirsk Institute of Chemical Biology and Fundamental Medicine (ICBFM) SB RAS and Krasnoyarsk Institute of Biophysics SB RAS presented a system that detects antibodies - markers of multiple sclerosis, reports TASS . It is known, symptomatically, that multiple sclerosis does not make itself felt immediately.
Clinical manifestations are typical for the stages when the disease has progressed quite strongly. And the effectiveness of therapy strongly depends on the earliest possible diagnosis. Maria Vorobyova, senior researcher at the RNA Chemistry Laboratory of the Institute of Chemical Biology and Fundamental Medicine of the SB RAS, commented: "In our work, a recognizing molecule and a luminous molecule are combined. At this stage, we have reliably demonstrated the possibility of detecting antibodies in patient sera."
These are molecules based on nucleic acids (aptamers) that identify antibodies characteristic of multiple sclerosis. They were connected to systems based on photoproteins - luminous bioluminescent proteins. If the sample contains antibodies characteristic of multiple sclerosis, the bioluminescent protein will glow. This approach makes the diagnosis of the disease simple and accurate.